Overview

Simple Predictable Regeneration

Exactech is shaping the future of bone repair with Regenaform® and Regenafil® allograft. For nearly a decade, Exactech has been a leader in orthopaedic bone regeneration. Now, these materials are offering simple and predictable results to dental professionals around the world.

Clinically proven in a variety of applications, Regenaform and Regenafil are the natural choices for biological bone repair.

Simple

Regenaform and Regenafil Allograft Pastes are available in two prepackaged modalities–Room Temperature and Frozen–to meet your personal preference.

When warmed, Regenaform and Regenafil Frozen become soft and moldable yet return to a resilient solid at body and room temperature. Simply shape and fit it into the site; the materials adapt to the defect morphology.

Regenaform and Regenafil Room Temperature (RT) can be hydrated chairside with a variety of diluents and are available for use within 60 seconds. This eliminates the need for a water bath and freezer.

Regenaform and Regenafil are available in a wide range of sizes. This maximizes the precious gift of human tissue by reducing waste. Whether you use Regenaform and Regenafil Frozen or Room Temperature, they both offer the advantage of exceptional handling and stability at the graft site.

Predictable Regeneration

Both Regenaform and Regenafil contain demineralized bone matrix (DBM), also known as DFDBA (demineralized freeze-dried bone allograft), which, through osteoinduction provides for the formation and development of bony tissue.¹ Regenaform also contains mineralized cortical cancellous bone chips, which provide for osteoconductivity.²

DBM from each donor is implanted in a scientifically-proven in vivo rat model to confirm inductivity (Urist’s standard model). Only material that is demonstrated by its histology to exceed minimum osteoinductive standards is used. That means predictable performance.*

References

1. Urist M.R. Bone: Formation by Autoinduction. Science, 1965. 150(3698): pp. 893-899.
2. Goldberg V., et al., Biology of autografts and allografts. In Bone and Cartilage Allografts: Biology and Clinical Applications. Edited by V. Goldberg and G. Friedlaender. Park Ridge, IL, American Academy of Orthopaedic Surgeons, 1989, p. 3.

*Finished product induced bone formation when implanted in a modified athymic nude rat assay. Findings from an animal model are not necessarily predictive of human clinical results.