Oralife DMB

• Demineralized bone matrix (DBM, DFDBA)
• Oralife DBM averages retained calcium levels of less than 2 percent¹
• DBM allows the recruitment of mesenchymal cells to the defect site and stimulation of those cells to form new bone²
• DBM is made up of the organic portion of bone and includes naturally occurring growth factors including bone morphogenic protein (BMP)^3,4

Oralife 50:50 Cortical/Cancellous Mix

• Oralife 50:50 provides the convenience of a pre-mixed mineral retained cortical and cancellous product with the benefits of each component
• Known benefits of cortical and cancellous particulate include mechanical stability, strength and volume through a conductive lattice, as well as varied regeneration times due to the faster infiltration of blood cells and remodeling of the cancellous portion⁵
• Oralife 50:50 particles range from .25mm to 1mm

Oralife Plus Combination Allograft

• A mixture of DBM with mineral-retained cortical and cancellous chips, processed in a manner to retain the naturally occurring growth factors (BMP), and a conductive lattice—all in one product^3,4,6
• Cost-effective alternative to completely engineered grafting materials
• Design rationale is based on previously proven ratios of our engineered biologic allograft, just excluding the carrier
• Available in DBM plus .25 - 1mm chips and DBM plus 1 - 2mm chips

Oralife Cancellous Particulate  

• Cancellous particulate is known to provide an excellent matrix for the infiltration of blood cells, facilitating the remodeling process that leaves behind healthy, natural bone²

Oralife Cortical Particulate

• Cortical particulate is known to offer both structural strength and space maintenance, and adds volume during the bone remodeling stage of osseous regeneration through its natural osteoconductive properties⁵

All Oralife products are single donor grafts that are recovered and processed in accordance with FDA and AATB guidelines, using Allowash^® Technology. Oralife products are aseptically-processed human allografts that are pre- and post-processing microbial tested. Oralife allografts may be shipped and stored at ambient temperature and do not require refrigeration or frozen storage.

Product Application

References

1. Data on file at Exactech.

2. Kalfas I. Principles of bone healing. Neurosurg Focus. 10(4):Article 1, 2001 

3. McAllister BS, Hagnignat K. Bone augmentation techniques. J Periodontal. 2007 Mar; 78(3):377-96.

4. Blum B, Moseley J, Miller L, Richelsoph K, Haggard W. Measurement of bone morphogenetic proteins and other growth factors in demineralized bone matrix. Orthopedics. 2004 Jan;27(1 Suppl):s161-5.

5. Friedlaender GE, Goldberg VM (eds). Bone and Cartilage Allografts: Biology and Clinical Application. Park Ridge, IL: American Academy of Orthopaedic Surgeons, 1991.

6. Data on file at LifeNet Health. Allowash Brochure.