Features & Benefits
Features & Benefits of Optefil® & Opteform®
Features and Benefits
Opteform
- Osteoinductive1

- Osteoconductive2
- Osteogenic1, when mixed with blood
- Formable to any shape
- Becomes a resilient solid
- Non-water soluble—won’t wash away
- Terminally sterilized
- Every lot tested for quality and safety
Optefil
- Osteoinductive1*
- Osteogenic1, when mixed with blood
- Formable, flowable—can be delivered with syringe into graft site or molded into shape
- Becomes a resilient solid
- Non-water soluble—won’t wash away
- Terminally sterilized
- Every lot tested for quality and safety
Constituents
Opteform
- Demineralized Bone Matrix (DBM)
- Cortical Cancellous Bone Chips
- Gelatin Carrier
Optefil
- Demineralized Bone Matrix (DBM)
- Gelatin Carrier
Surgical Indications
Opteform and Optefil are bone void fillers often used in applications such as...
Oncology — Giant Cell Tumors • Bone Cysts • Benign & Malignant Tumors • Total Joint — Acetabular Impaction Grafting • Sloof Technique • Ring/Cage Revisions • Fractures • Contained and Uncontained Defects • Osteotomies • Revisions • Osteolytic Defects • Trochanteric Fractures •Non-unions • Joint Fusion • Condylar Defects • Proximal Tibial Defects • Avascular necrosis • Iliac Crest Graft Backfill • On-lay with Femoral Struts • AVN — Calcaneous • Talus • Femoral Head • Foot and Ankle — Talus and Calcaneal Fractures • Joint Fusion • Lisfranc Procedures • Pilon Fractures • Osteotomies: Opening & Closing Wedge, Translational • Primary and Revision Arthrodesis: Pan Taylor, Ankle, Triple, Double, Isolated Hindfoot, Forefoot, Midfoot • Sports Medicine — Wedge Opening HTO • ACL/PCL Reconstructions • Hand — Osteotomies: Opening & Closing Wedge, Translational • Joint Fusion • Distal Radius & Scafoid Fractures • Non-unions • Upper Extremity — Supracondular & Comminuted Fractures • Non-Unions • Trauma — Long Bone Fractures (Open and Closed) • Non-unions • Segmental Defects with External Fixation • Tibial Plateau & Pilon Fractures • Contained and Uncontained Defects.
References
1. Urist, M.R., Bone: Formation by Autoinduction. Science, 1965. 150(3698): pp. 893- 899.
2. Goldberg, V. et al., Biology of autografts and allografts. In Bone and Cartilage Allografts: Biology and Clinical Applications. Edited by V. Goldberg and G. Friedlaender. Park Ridge, IL, American Academy of Orthopaedic Surgeons, 1989, p. 3.
*Finished product induced bone formation when implanted in a modified athymic nude rat assay. Findings from an animal model are not necessarily predictive of human clinical results.

