• Osteoinductive*
• Osteoconductive
• Osteogenic when mixed with blood or ABG
• Always formable
• Resists migration from graft site
• Each lot tested for sterility
  
• DBM tested in-vivo for osteoinductivity
• Delivered and stored dry to maintain the bioactivity of the DBM
• Concentration studies prove optimal new bone forming potential¹
• Can be mixed one-to-one with autogenous bone
• Hydrophilic carrier with potential to absorb and retain autogenous growth factors
• Mix with different volumes and different diluents to create indication-specific handling requirements
  

Constituents

1) Demineralized Bone Matrix (DBM)

• Optimal 81 percent concentration of DBM by dry weight¹
• Each lot tested for sterility
• Each lot tested in-vivo for proven OI potential
  

2) Cortical Cancellous Bone Chips

• 1-3.3mm size range
• Densely packed for mechanical load sharing
  
• Gamma Irradiated

3) Resorbable Hydrogel Carrier

• Intra-operative flexibility to craft handling characteristics
• Resistant to migration from graft site
• Ethylene Oxide sterilized
  

Surgical Indications

Optecure’s cleared indications include use as a bone graft extender in the extremities, spine and pelvis or used alone as a bone void filler in extremities and pelvis.

*Finished product induced bone formation when implanted in an athymic nude mouse assay. Findings from an animal model are not necessarily predictive of human clinical results.

 References

1. Keller T, et al. Carriers may change osteoinductivity of human demineralized bone in the athymic mouse. The 32nd annual Meeting and Exhibition of the American Academy of Dental Research. 2003 Mar.